Lepra tuberculoide. Rios González, Carlos Miguel Cátedra de Dermatología. Facultad de Ciencias Médicas. Universidad Nacional de Caaguazú. Paraguay. El 65,4 % de los casos índices fueron hombres y 22 (84,6 %) lepromatosos; dos tenían lepra indeterminada y dos tuberculoide. Los casos secundarios fueron. La lepra o malaltia de Hansen és una malaltia infectocontagiosa però difícilment . que estaran engruixits i es podran palpar, sobretot a la lepra tuberculoide.

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However, those which settle in the internal organs are usually effectively eliminated by macrophages.

Tubercuooide Rev Mex ; As few bacilli are found in the lesions of this clinical form it is known as paucibacillary. The rhinomaxillary syndrome in leprosy: He lives with his wife, a daughter and five grandchildren.

He attended a long-stay unit during the summer of for a limited period two months in order to provide family respite. Smithsonian Institution Press; El-orf, A, Stugh AM. This rhinomaxillary syndrome only corresponds to the lepromatous form of leprosy 7which is lepfa suffered by the patient described here Figure 1 and, most likely, was what affected his close relatives. N Engl J Med ; The deep infections lead to perforation of the septum, and their spreading to the surface of the hard palate tubeculoide cause periostitis that is visible on X-rays.

Medicina Interna, Tomo I.

Lepra lepromatosa: Revisión y caso clínico

Beginning at the midline, the maxillary bone begins to erode leprz the extent that the palate becomes perforated. These lesions sometimes bleed to the extent that medical tubedculoide is required. The swollen upper eyelids create a sleepy appearance and the repercussions in the supraorbital tissues usually lead to the loss of eyebrow hair, particularly in lateral areas.

International Journal of Osteoarchaelogy ; 2: In addition to these polar leprw of immune response, a significant number of patients show a partial or incomplete response and present borderline forms of the disease. Centro Hospitalar do Porto. Around one-third of people with leprosy present the first clinical manifestations during childhood.


Inthe WHO attempted to describe these degrees of semi-quantitative response, designating them as borderline tuberculoid BT and borderline lepromatous BL In spite of ongoing, prolonged contact, conjugal leprosy is not frequent and requires several years to tuberculoiide in the second person.

This invasion usually occurs indirectly, via lesions in the surrounding soft tissues or, less often, via the blood. Therefore, it seemed of interest to review the topic by means of a highly representative clinical case.

Quinolones, such as ofloxacin and pefloxacin, tuberculoie well as some macrolides, such as clarithromycin and minocyclin, are also effective. In addition to traumatic lesions, the loss of cutaneous tissue favours pyogenic infections, ulcers and spreading to deeper tissues. Our patient showed generalized changes in pigmentation, as can be seen in the figures.

Lepromatous leprosy usually begins in the form of chronic rhinitis.

Dermatology Online Journal

The skin areas anaesthetised by the nerve infection are susceptible to tissue infection. Determining the occurrence of leprosy amongst couples and establishing the type of leprosy in index and secondary cases.

There may also be destruction of the anterior maxilla and loss of teeth. Lepr Rev ; Nature Genet ; Lepromatous rhinitis may spread to the maxilla and be complicated by secondary pyogenic infections. The facial skin shows areas of localized swelling, with deep furrows between them.

The mean age at diagnosis was 52 years, and sensory symptoms predominate as neurological manifestation of disease. Although the trunk may be affected, few lesions are generally observed in this region 1.

The bilateral amaurosis and hypoacusia were noted. Studying by a new thecnics, which he baptised before as “Lleras’ method”, the scarching of the agent of leprosy in tuberculoid cases, by examination of sub-corium lymph obtained from the lesion, he discovered new forms of the Hansen bacillus, which describes briefly, arriving at the following conclusions: This was not the case of the patient reported here, who maintained sensitivity.

Despite tubercuooide problems the tendency of the disease to preserve the main viscera means that life expectancy is barely reduced. The peripheral nerves are usually affected by the bacillus in lepromatous leprosy.


In addition to the facial lesions described above it is common to find multiple skin macules in cooler areas of the body extremities, buttocks. ReadCube Visualizar o texto. The diagnosis, based on clinical suspicion, is confirmed through tuberckloide and histopathological analyses, as well as by means of the lepromin test intradermal reaction that is usually negative in lepromatous leprosy form and positive in the tuberculoid form.

They were aged from 20 to Blood tests upon admission corroborated the anaemic state and the hepatic and renal alterations indicated previously.

Its preference for cooler anatomical regions means that vital organs are usually preserved, but also makes leprosy a disease that slowly destroys the distal areas of fingers and toes and causes nasal and facial deformities that lead to social marginalization. However, as positive results are also obtained tuberculpide patients without leprosy this test only serves to assess the immunological state in already-diagnosed patients 1,6.

Patients with tuberculoude leprosy are highly infectious, although most exposed immunocompetent individuals do not contract the disease. Disabilities were more common in the feet and to a higher degree in lepromatous index cases who had had the disease for a longer time than the secondary cases because these were more frequently paucibacillary patients who had tubdrculoide disease having shorter evolution. This consists in the intradermal injection of lepromin extract of the leprous bacillus taken from sick patients.

Lepromatous leprosy in index cases was more frequently associated with leprosy in the couple. Conyugal leprosy among Libian patients.