HEREDITARY GINGIVAL FIBROMATOSIS PDF

Hereditary gingival fibromatosis (HGF), also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. HGF is characterized as a . Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported . Hereditary gingival fibromatosis can occur as an isolated. Mutation in SOS1, son-of-sevenless gene, is thought to be responsible for hereditary gingival fibromatosis. This report shows a case of.

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The case presented in this paper differs from previous reports since she needed combined orthodontic and orthognathic treatment because of severe skeletal discrepancies of the jaws. Based on the provisional diagnosis, an incisional biopsy was done and sent for histopathological examination to confirm the diagnosis.

Hereditary gingival fibromatosis: Characteristics and treatment approach

It can be isolated, with autosomal dominant inheritance, or as part of a syndrome. J Oral Maxillofac Surg.

Hereidtary glands Benign lymphoepithelial lesion Ectopic salivary gland tissue Frey’s syndrome HIV salivary gland disease Necrotizing sialometaplasia Mucocele Ranula Pneumoparotitis Salivary duct stricture Salivary gland aplasia Salivary gland atresia Salivary gland diverticulum Salivary gland fistula Salivary gland hyperplasia Salivary gland hypoplasia Salivary gland neoplasms Benign: Please review our privacy policy.

Routine investigation was done and incisional biopsy performed. Secretor status and carriage of Neisseria species. Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.

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Hereditary gingival fibromatosis: Characteristics and treatment approach

Genetic linkage studies have found to localize genetic loci for autosomal dominant forms of HGF to chromosome 2pp22 indicative of HGF1 and chromosome 5qq22 indicative of HGF2. The affected gingival tissue is pink, usually shows exaggerated stippling, and is firm and fibrous on palpation which helps to differentiate the condition from drug-induced gingival enlargements in those where the tissue is often movable [ 13 ]. Source 1 Later on inthere was a case study done on a year-old male with severe gingival overgrowth, almost covering all fibromatsois.

B Stage of eruption: Unilateral gingival fibromatosis with localised aggressive periodontitis involving first molars: Here, an interesting case report of massive HGF has been presented.

Two types of fibroblasts are present in HGF: Epidemiology, pathogenesis and complications. Dilantin intoxication without dilantin. The patient and her parents noticed gingival enlargement when she was seven years old with gradual spacing of teeth. A scanty amount of plaque and food debris was entrapped into the posterior teeth which were partially visible amongst the entire dentition with no significant inflammation present around them.

Footnotes Source of Support: The patient narrated that she often used to chew food with her gums and never used to practice oral hygiene measures.

The enlargement is usually painless and may extend up to the mucogingival junction but does not affect the alveolar mucosa[ 910 ] or alveolar bone.

Mutation in SOS1, son-of-sevenless gene, is thought to be responsible for hereditary gingival fibromatosis. A case of fibromatosis gingivae. Hereditary fibrous hyperplasia of the gingiva with varying penetrance and expressivity.

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Gimgival gingival fibromatosis associated with generalized aggressive periodontitis: Some researchers suggest that HGF is transmitted as a Mendelian trait since both autosomal dominant and autosomal recessive transmission has been reported since the early s.

The enlarged gingival tissue appears firm and pink with exaggerated stippling.

Ginival comments written in English can be processed. Am J Hum Genet ; In some cases it shows only minimal involvement characterized by enlargement of the tuberosity area and buccal gingiva around the mandibular molars; however, in severe form it can involve both maxillary and mandibular gingiva.

Syndromes of head and neck.

Hereditary gingival fibromatosis – Wikipedia

gibromatosis Few studies have documented the use of carbon dioxide laser,[ 27 ] however, the most widely used method of removing large quantities of tissue is the conventional external bevel gingivectomy with gingivoplasty particularly when there are pseudo pockets and no attachment loss. The treatment consists of surgical excision of the enlarged tissue; often in a series of gingivectomies, that should be complemented by an effective program of oral hygiene.

If the enlargement is present before tooth eruption the dense fibrous tissue may interfere with or prevent the eruption. Her parents did not reveal any evidence of gingival overgrowth. Role of c-myc proto-oncogene in the proliferation of hereditary gingival fibromatosis fibroblast. Idiopathic gingival fibromatosis case report.